Tag Archives: Depression

Perinatal Depression and Anxiety: How Long Does It Last?

In the earliest studies, postpartum depression was described an episode of depression associated with childbirth, typically emerging within the first three months after delivery.  As more research has been carried out, we have learned that a sizeable number of women with PPD actually begin to experience symptoms during pregnancy.  The bottom line is that women… Read More »

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »