Tag Archives: Failure

Pfizer, Merck KGaA's Bavencio takes a hit with second ovarian cancer failure

Back in November, Pfizer and Merck KGaA reported that immuno-oncology drug Bavencio had failed a late-stage ovarian cancer trial. And now the companies can make it two. Friday, the partners said they’d scrapped a phase 3 study examining Bavencio in combination with and/or after chemo in previously untreated patients after the drug showed it couldn’t… Read More »

Low Tidal Volume Ventilation Trial in Acute Respiratory Failure Not Feasible

December 17, 2018 Share this content: The trial would need to enroll approximately 107,373 patients to have a 96% power to detect a 3% improvement in mortality at 80% to 100% adherence to low tidal volume ventilation. A cluster-randomized clinical trial of low tidal volume ventilation vs usual care in patients with acute respiratory failure… Read More »